November 12, 2026
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Eli Lilly Shares Climb on Positive Clinical Trial Data and Expanded Access

💼 Investing 2 min read 👁 0

Eli Lilly shares rose following successful phase 3 trial results for its GLP-1 drugs in treating osteoarthritis and sleep apnea. The company also announced a partnership to increase distribution of its weight-loss medications.

Eli Lilly Shares Climb on Positive Clinical Trial Data and Expanded Access💼Investing

Photo: Motley Fool

Key points

  • Retatrutide trials showed 25% weight loss and 50% reduction in osteoarthritis pain.
  • Foundayo demonstrated a 44% reduction in sleep apnea breathing interruptions.
  • Full-year revenue guidance was raised to between $91 billion and $92 billion.

Eli Lilly shares trended upward early this week following a series of positive clinical developments and strategic partnerships. The company reported that its experimental drug, retatrutide, demonstrated significant efficacy in phase 3 trials, showing an average 25% body weight reduction and a 50% decrease in knee osteoarthritis pain among participants. Researchers noted that the drug's anti-inflammatory properties likely contribute to these joint health improvements.

In addition to these findings, Eli Lilly announced that its weight-loss medication, Zepbound, and its drug Foundayo will see expanded distribution through a new agreement with the Hims & Hers Health platform. Further clinical success was reported for Foundayo, which showed a 44% reduction in breathing interruptions for patients with obstructive sleep apnea. The company intends to submit this data to the FDA for a new treatment indication by the end of the year.

The company’s financial performance remains strong, with third-quarter revenue climbing 39% to $24.4 billion. Management has subsequently raised its full-year revenue guidance to a range of $91 billion to $92 billion. Following these updates, analysts at Jefferies increased their price target for the stock to $1,700.

What to watch next: Investors should monitor the upcoming FDA submission for Foundayo's sleep apnea indication and further research regarding the potential of GLP-1 drugs to treat cardiovascular and metabolic disorders.

Source Motley Fool — fool.com/investing/2026/11/12/more-good-news-for-eli-lilly-sends-th… ↗

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